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Cholesterol Issues

Clinical Trials  |  Add a link  |  Regulations  |  Discussion Board  |  Ask the Nurse | Last Update January 1st. 2009  |  About FDA.COM  | Media Kit

What is Cholesterol?

  • Cholesterol is a fat-like material in your blood. Your body makes its own cholesterol. When you eat foods that have lots of fat or cholesterol, you can have too much cholesterol in your blood.
  • Cholesterol can build up on the inside the blood vessels of your heart. If too much cholesterol builds up, then the blood cannot flow through to your heart. This can cause a heart attack.

Good vs. Bad Cholesterol

Not all cholesterol in your blood is bad for you. There are three kinds of blood cholesterol that you should know about: HDL (good cholesterol), LDL (bad cholesterol) and triglycerides.

What can you do?

There are things that you can do to lower your cholesterol.

  • Cut back on foods with lots of fat such as fatty meats, fried foods, whole milk, fatty cheeses, butter, margarine, oils, lard, and creams.
  • Cut back on food with lots of cholesterol, such as egg yokes and whole eggs.
  • Eat more fruits and vegetables.
  • Cut back on fatty snacks and desserts, such as candy, cookies, doughnuts, muffins, pastries and pies.
  • Exercise at least 30 minutes most days.
  • If you are overweight, try to lose weight. Try to lose weight by cutting back on the amount that you eat. Even a small amount of weight loss can help lower your bad cholesterol, and you will also help your health in other ways.
  • Ask your doctor if you need to take medicine to help lower your cholesterol. Triglycerides are another form of fat in your blood. They can also raise your risk for heart disease. Levels that are borderline high (150-199 mg/dL) or high (200 mg/dL or more) may need treatment.

What are the warning signs of high blood cholesterol?

  • Most people do not have any signs.
  • Sometimes cholesterol can build up in the blood vessels of your heart and cause chest pains.

How do you find out if you have high cholesterol?

  • Go to the doctor and ask for a cholesterol test. The test will let you know how much good and bad cholesterol you have.
  • The doctor will tell you the number for your total cholesterol level.
  • Your total cholesterol number should be under 200.
Good Cholesterol Bad Cholesterol
Good cholesterol is called HDL Bad cholesterol is called LDL
Helps to keep the arteries from clogging up Causes the build up in your arteries and cause blockages of your arteries
Protects against heart disease Causes heart disease
Good level = 60mg/dL or more Good level = under 100mg/dL

To learn more:

National Heart, Lung, and Blood Institute Health Information Center
Phone: 301-592-8573
www.nhlbi.nih.gov/health/infoctr/index.htm

The National Women's Health Information Center
Phone: 1-800-994-WOMAN (1-800-994-9662)
1-888-220-5446 for the hearing impaired
www.4women.gov/faq/cholesterol.htm

 

 

Sign up now for the LIPITOR 30-Day Trial

Reference Links - Add a link

Clinical Trials - Add a clinical trial

 top
1
Recruiting
Egg Cholesterol Consumption, Blood Cholesterol and Skeletal Muscle Hypertrophy
Conditions:
Sarcopenia;   Cardiovascular Disease 
Intervention:
Behavioral: resistance training with dietary cholesterol administration 
 
 

 
2
Recruiting
Effect of Niaspan on Cholesterol in Men
Condition:
HDL Cholesterol 
Intervention:
 
 
 

 
3
Recruiting
Genetic Polymorphysm of Cholesterol 24 S Hydroxylase in Patients With Glaucoma and AMD
Condition:
Glaucoma 
Interventions:
Biological: Assessing the blood level of cholesterol 24 S Hydroxylase;   Biological: Assessing the blood level of cholesterol 24 S hydroxylase;   Biological: assessing the blood level of cholesterol 24 S hydroxylase 
 
 

 
4
Recruiting
Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency
Conditions:
Mevalonic Aciduria;   Mevalonate Kinase Deficiency;   Immune System Diseases;   Periodic Fever Syndromes, Hereditary;   Lipid Metabolism, Inborn Errors 
Intervention:
 
 
 

 
5
Recruiting
ROCKET I - Randomized Open Label Switch for Cholesterol Elevation on Kivexa Evaluation Trial
Condition:
HIV Infections 
Interventions:
Drug: Atripla;   Drug: Kivexa plus Sustiva 
 
 

 
6
Recruiting
ROCKET II - Randomized Open Label Switch for Cholesterol Elevation on Kivexa + Kaletra Evaluation Trial
Condition:
HIV-1 
Interventions:
Drug: Truvada (emtricitabine 200 mg/tenofovir DF 300 mg) and Kaletra (lopinavir 200 mg/ritonavir;   Drug: Kivexa (abacavir (as sulfate) 600 mg/lamivudine and Kaletra (lopinavir 200 mg/ritonavir 
 
 

 
7
Recruiting
Short-Term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome
Condition:
Smith-Lemli-Opitz Syndrome 
Intervention:
Drug: Cholesterol Suspension 
 
 

 
8
Recruiting
Ezetimibe Reverse Cholesterol Transport (RCT) Pilot Study
Condition:
Hypercholesterolemia 
Interventions:
Drug: ezetimibe;   Drug: Placebo 
 
 

 
 
 
11
Recruiting
The Effect of Plant Sterol Supplement on Blood Cholesterol
Condition:
High Blood Cholesterol Level 
Intervention:
Behavioral: Intake of plant sterols 
 
 

 
12
Recruiting
Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-Density Lipoprotein (LDL) Cholesterol
Condition:
Hypercholesterolemia 
Interventions:
Drug: Vytorin;   Drug: Simvastatin 
 
 

 
13
Recruiting
A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease
Condition:
Hypercholesterolemia 
Interventions:
Drug: ezetimibe (+) simvastatin;   Drug: Comparator: atorvastatin;   Drug: Comparator: Placebo (unspecified);   Drug: Comparator: Placebo (unspecified) 
 
 

 
14
Recruiting
Gallbladder Cholesterolosis, Body Mass Index and Serum Cholesterol and Triglycerides
Conditions:
Gallstones;   Gallbladder Cholesterolosis;   Serum Cholesterol and Triglycerides;   Body Mass Index 
Intervention:
Other: Biopsies and Laboratory tests 
 
 

 
15
Recruiting
 

 
16
Recruiting
The Anti-Diabetic and Cholesterol-Lowering Effects of Cinnamon and Cassia Bark
Conditions:
Type 2 Diabetes;   Hypercholesterolemia 
Interventions:
Dietary Supplement: Cinnamonforce;   Dietary Supplement: Placebo 
 
 

 
17
Recruiting
Crossover of Higher Dose Statins in Patients With Low High-Density Lipoproteins Cholesterol (HDLc)
Condition:
HDL Cholesterol 
Interventions:
Drug: Simvastatin;   Drug: Atorvastatin 80 mg 
 
 

 
18
Recruiting
ABT-355 Reverse Cholesterol Transport (RCT) Study
Condition:
Dyslipidemia 
Intervention:
Drug: ABT-335 
 
 

 
19
Recruiting
Study of 3,5-Diiodothyropropionic Acid (DITPA) in Hypercholesterolemic Patients
Condition:
Hypercholesterolemia 
Intervention:
Drug: 3,5-Diiodothyropropionic acid (DITPA) therapy 
 
 

 
20
Recruiting
Effects of a Long Term Dietary Portfolio and of Sequential Removal of Food Components From the Diet
Conditions:
Hyperlipidemia;   Cardiovascular Diseases;   Hypercholesterolemia 
Intervention:
Procedure: Dietary portfolio of cholesterol-lowering foods 
 
 

 
21
Recruiting
Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study
Condition:
Acute Myocardial Infarction 
Intervention:
Drug: Pravastatin 
 
 

 
22
Recruiting
Improving Metabolism With HDL Cholesterol
Condition:
Heart Disease 
Intervention:
Drug: rHDL 
 
 

 
23
Recruiting
Phase II Study of Dietary Cholesterol for Smith-Lemli-Opitz Syndrome
Condition:
Smith-Lemli-Opitz Syndrome 
Intervention:
Behavioral: diet 
 
 

 
24
Recruiting
The Use of Magnesium to Improve Blood Pressure, Cholesterol, and Glucose Control
Conditions:
Coronary Artery Disease;   Hypertension;   Dyslipidemia;   Diabetes 
Intervention:
Drug: magnesium L-lactate 
 
 

 
25
Recruiting
Dietary Protein and Insulin Sensitivity Study
Conditions:
Insulin Resistance;   Type 2 Diabetes;   Metabolic Syndrome;   Cardiovascular Disease;   Dyslipidemia 
Intervention:
Other: Diet (increased protein intake) 
 
 

 
26
Recruiting
Effect of Plant Sterols Esterified to Fish Oil Fatty Acids on Plasma Lipid Levels
Condition:
Dyslipidemia 
Intervention:
Dietary Supplement: Plant sterols esterified to fish oil fatty acids 
 
 

 
27
Recruiting
A Multicenter, Active and Placebo-Controlled Study of Enteric Coated Sevelamer in Patients With Mild to Moderate Hypercholesteremia
Condition:
Hypercholesterolemia 
Interventions:
Drug: Enteric coated sevelamer;   Drug: Enteric coated sevelamer;   Drug: Colesevelam Cholestagel;   Drug: Placebo;   Drug: Placebo 
 
 

 
28
Recruiting
A Patient-Spouse Intervention for Self-Managing High Cholesterol
Condition:
Hypercholesterolemia 
Intervention:
Behavioral: patient-spouse self-management 
 
 

 
29
Recruiting
Drug Transport in Patients With Anorexia Nervosa
Condition:
Anorexia Nervosa 
Intervention:
 
 
 

 
30
Recruiting
Combined Effects of Non-Statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study
Condition:
Atherogenic Dyslipidemia 
Interventions:
Drug: Lipitor;   Drug: ABT335;   Drug: Niaspan 
 
 

 
31
Recruiting
The Influence of Dietary Plant Sterols and Plant Stanols on Cholesterol and Plant Sterol Levels in Atheromatous Plaques
Condition:
Atherosclerosis 
Interventions:
Dietary Supplement: Plant Stanol;   Dietary Supplement: Plant Sterol 
 
 

 
32
Not yet recruiting
Safety and Efficacy Study Comparing ABT-143 to Simvastatin in Subjects With Elevated Levels of Low Density Lipoprotein Cholesterol ("Bad Cholesterol") and Triglycerides
Conditions:
Dyslipidemias;   Hypercholesterolemia;   Coronary Heart Disease;   Hypertriglyceridemia 
Interventions:
Drug: ABT-143;   Drug: simvastatin 
 
 

 
33
Recruiting
Heart Outcomes Prevention Evaluation–3
Conditions:
Cardiovascular Disease;   Stroke 
Interventions:
Drug: rosuvastatin calcium (10mg);   Drug: candesartan cilexetil (16mg) / hydrochlorothiazide (12.5mg) 
 
 

 
34
Recruiting
 

 
35
Recruiting
High-Density Lipoprotein (HDL) Cholesterol in Women Taking Tibolone
Condition:
HDL Cholesterol 
Interventions:
Drug: fenofibrate and tibolone;   Drug: tibolone 
 
 

 
36
Recruiting
Impact of HIV and Its Treatment on Reverse Cholesterol Transport
Condition:
HIV Infections 
Intervention:
 
 
 

 
37
Recruiting
Effects of Vitamin D on Lipids
Condition:
Hypercholesterolemia 
Interventions:
Drug: Vitamin D2;   Drug: Vitamin D3;   Drug: Placebo 
 
 

 
38
Recruiting
Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE
Conditions:
Cardiovascular Disease;   Peripheral Arterial Disease;   Diabetes Mellitus;   Coronary Heart Disease 
Interventions:
Drug: ER niacin/laropiprant;   Drug: simvastatin;   Drug: ezetimibe 
 
 

 
39
Recruiting
Phase I Study of IV DOTAP: Cholesterol-Fus1 in Non-Small-Cell Lung Cancer
Condition:
Lung Cancer 
Intervention:
Genetic: DOTAP:Chol-fus1 
 
 

 
40
Recruiting
Portfolio 5 - Multicentre
Conditions:
Hyperlipidemia;   Cardiovascular Disease 
Intervention:
Behavioral: Effects of a self-selected dietary portfolio on cholesterol reduction 
 
 

 
41
Recruiting
Standard Process 21 Day Purification Program Project
Condition:
Hyperlipidemia 
Interventions:
Other: Standard Process 21 Day Purification Program (SPPP);   Other: Standard Process 21 Day Purification Program (SPPP) 
 
 

 
42
Recruiting
Simvastatin Therapy in Smith-Lemli-Opitz Syndrome
Condition:
Smith-Lemli-Opitz Syndrome 
Interventions:
Drug: Simvastatin Susp.;   Drug: OraPlus 
 
 

 
43
Not yet recruiting
Safety and Effectiveness of Atorvastatin in HIV Infected Children and Adolescents With Hyperlipidemia
Conditions:
HIV Infections;   Hyperlipidemia 
Intervention:
Drug: Atorvastatin 
 
 

 
44
Recruiting
Preliminary Study of Safety and Efficacy of Policosanol
Conditions:
HIV-Related Dyslipidemia;   HIV Infections 
Interventions:
Dietary Supplement: Policosanol;   Dietary Supplement: Placebo 
 
 

 
45
Recruiting
A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as Add-on Therapy to Their Existing Medication
Condition:
Familial Hypercholesterolemia 
Interventions:
Drug: Colesevelam hydrochloride film-coated tablets;   Drug: Placebo 
 
 

 
46
Not yet recruiting
The Effect of Lapaquistat Acetate on Blood Cholesterol Levels
Condition:
Hypercholesterolemia 
Interventions:
Drug: Lapaquistat acetate (TAK-475);   Drug: Placebo 
 
 

 
47
Recruiting
DNA Diagnostic System for Statin Safety and Efficacy
Conditions:
Hypercholesterolemia;   Myopathy 
Intervention:
 
 
 

 
48
Not yet recruiting
Antiepileptic Drugs and Vascular Risk Markers
Condition:
Subarachnoid Hemorrhage 
Interventions:
Drug: phenytoin;   Drug: valporate;   Drug: levetiracetam 
 
 

 
49
Recruiting
Safety and Efficacy Study of AEGR-733 in Patients With Homozygous Familial Hypercholesterolemia (FH)
Condition:
Homozygous Familial Hypercholesterolemia 
Intervention:
Drug: AEGR-733 
 
 

 
50
Recruiting
Study to Assess If Internet-Based Tailored Advice Could Modify Behaviour to Improve Health
Condition:
Hypercholesterolemia 
Intervention:
Behavioral: Internet-based tailored advice on cardiovascular risk 
 
 
51
Recruiting
STOP CAP: Pravastatin and Atorvastatin to Prevent Heart Disease in People With High Cholesterol Level, Diabetes or Metabolic Syndrome
Conditions:
Diabetes Mellitus;   Metabolic Syndrome X;   Hypercholesterolemia 
Interventions:
Drug: Atorvastatin;   Drug: Pravastatin 
 
 

 
52
Recruiting
A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)
Condition:
Homozygous Familial Hypercholesterolemia 
Intervention:
Drug: AEGR-733 
 
 

 
53
Recruiting
Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis
Condition:
Cerebrotendinous Xanthomatosis 
Interventions:
Drug: chenodeoxycholic acid;   Drug: lovastatin 
 
 

 
54
Recruiting
 

 
55
Recruiting
Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets
Conditions:
Hyperlipidemias;   Atherosclerosis;   Coronary Heart Disease;   Carotid Stenosis;   Peripheral Vascular Diseases;   Diabetes Mellitus 
Intervention:
Drug: Any cholesterol-lowering drug 
 
 

 
56
Recruiting
The Effect of Dietary Sitosterol on Blood Sugar and Cholesterol
Condition:
Sitosterolemia 
Intervention:
Behavioral: High/Low Sitosterol 
 
 

 
57
Recruiting
Exercise Versus Extended-Release Niacin in Patients With Coronary Heart Disease and Low High-Density Lipoproteins (HDL) Cholesterol: Effect on Lipid Profile and Endothelial Function
Conditions:
Coronary Disease;   Hypolipoproteinemia 
Interventions:
Behavioral: physical exercise;   Drug: niaspan (extended-release niacin);   Drug: niacin;   Other: control 
 
 

 
58
Recruiting
Family Heart Health Program: Randomized, Controlled Trial
Condition:
Coronary Heart Disease 
Intervention:
Behavioral: 12-week risk reduction program, managed by a Heart Health Educator 
 
 

 
59
Recruiting
U-CHAMP: Urban Calgary Cardiovascular Health Assessment and Management Program
Conditions:
Cardiovascular Diseases;   Hypertension;   Hyperlipidemia 
Intervention:
Other: participant referral to primary care network physician 
 
 

 
60
Recruiting
Study of Smith-Lemli-Opitz Syndrome
Conditions:
Abnormalities;   Inborn Errors of Metabolism;   Mental Retardation;   Muscle Hypotonia;   Smith Lemli Opitz Syndrome 
Intervention:
 
 
 

 
61
Recruiting
Diabetic Under 70 (Diabetics Below 70)
Conditions:
Diabetes;   Hyperlipidemia;   Atherosclerosis 
Intervention:
Drug: Any cholesterol-lowering drug 
 
 

 
62
Recruiting
Innovative Strategies For Risk Reduction Following CABG
Conditions:
Coronary Artery Disease;   Type II Diabetes Mellitus 
Intervention:
Behavioral: Consumption of Dietary Portfolio 
 
 

 
63
Recruiting
The Metabolic Effects of Different Weight Loss Diets
Conditions:
Metabolic Syndrome X;   Obesity;   Insulin Resistance;   Hypertension;   Diabetes 
Intervention:
Behavioral: The DASH diet vs the low glycemic index diet vs the average American diet 
 
 

 
64
Recruiting
Pioglitazone Vs Placebo in Combination With Niacin Extended Release on Low HDL
Condition:
Metabolic Syndrome 
Intervention:
Drug: Pioglitazone +/- placebo in combination with niacin ER 
 
 

 
65
Not yet recruiting
Flaxseed Intervention on Metabolic Syndrome
Condition:
Metabolic Syndrome X 
Interventions:
Dietary Supplement: flaxseed;   Behavioral: TLC diet education 
 
 

 
66
Recruiting
Safety, Pharmacokinetic Study of RVX000222 in Healthy Subjects and Subjects With Low HDL Cholesterol
Conditions:
Dyslipidemia;   Atherosclerosis;   Acute Coronary Syndrome;   Cardiovascular Disease 
Intervention:
Drug: RVX000222 (common name RVX-208) 
 
 

 
 
68
Recruiting
Inegy vs. the Doubling of Atorvastatin in High Risk Patients
Condition:
Hypercholesterolemia 
Interventions:
Drug: Comparator: ezetimibe/simvastatin 10/40 mg;   Drug: Comparator: atorvastatin 40 mg;   Drug: Comparator: atorvastatin 20 mg 
 
 

 
69
Recruiting
 

 
70
Recruiting
Omega-3 Fatty Acids for High Triglycerides in HIV-Infected Patients
Conditions:
HIV Infections;   AIDS;   Dyslipidemia;   Hypertriglyceridemia 
Intervention:
Procedure: Omega-3 fatty acid administration 
 
 

 
71
Recruiting
Hypolipemic Treatment in ACS: Antithrombotic Effects
Condition:
Acute Coronary Syndrome 
Interventions:
Drug: simvastatin;   Drug: ezetimibe;   Drug: placebo 
 
 

 
72
Recruiting
Effect of Policosanol as Monotherapy and Adjunctive to Statin Therapy
Condition:
High Cholesterol 
Interventions:
Drug: Policosanol;   Other: Placebo;   Drug: Policosanol Plus Already In Use Statin Therapy 
 
 

 
73
Recruiting
A Diabetes Study to Treat A Population Previously Not at Target
Condition:
Type 2 Diabetes 
Intervention:
Drug: Rosuvastatin 
 
 

 
74
Recruiting
The Effect of Lapaquistat Acetate on Blood Cholesterol Levels When Given With Statins
Condition:
Hypercholesterolemia 
Interventions:
Drug: Lapaquistat acetate (TAK-475) + statin;   Drug: Lapaquistate acetate (TAK-475) + Placebo 
 
 

 
75
Recruiting
A Study of MK6213 Co-Administered With Atorvastatin in Patients With Hypercholesterolemia
Condition:
High Cholesterol 
Interventions:
Drug: MK6213;   Drug: Comparator: atorvastatin calcium;   Drug: Comparator: placebo (unspecified) 
 
 

 
76
Recruiting
Effects of Ezetimibe Add-On to Statin Therapy on Adipokine Production in Obese and Metabolic Syndrome Patients With Atherosclerosis
Conditions:
Metabolic Syndrome;   Obesity;   Coronary Artery Disease 
Intervention:
Drug: Ezetimibe 
 
 

 
77
Recruiting
Using Magnetic Resonance Imaging to Evaluate Carotid Artery Plaque Composition in People Receiving Cholesterol-Lowering Medications (The CPC Study)
Conditions:
Coronary Artery Disease;   Carotid Artery Diseases;   Atherosclerosis 
Interventions:
Drug: Atorvastatin;   Drug: Extended Release Niacin;   Drug: Colesevelam;   Drug: Placebo Niacin;   Drug: Placebo Colesevelam 
 
 

 
78
Recruiting
Prospective Randomized Clinical Trial Evaluating the Impact of Vinegar on High Density Lipoprotein
Condition:
Cholesterol, HDL 
Interventions:
Dietary Supplement: Vinegar;   Other: Placebo 
 
 

 
79
Not yet recruiting
Reducing Weight and Diabetes Risk in an Underserved Population (STRIDE)
Conditions:
Weight Loss;   Diabetes Mellitus, Type 2;   Psychotic Disorders 
Intervention:
Behavioral: Premier Lifestyle Intervention with DASH Diet 
 
 

 
80
Recruiting
Multi-Arm Intervention Diabetes Adherence Study
Condition:
Diabetes 
Interventions:
Behavioral: Adherence information;   Behavioral: Adherence information plus motivational interviewing 
 
 

 
81
Recruiting
Efficacy Study of Pioglitazone/Metformin Combination Therapy in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia.
Conditions:
Diabetes Mellitus;   Dyslipidemias 
Interventions:
Drug: Pioglitazone and metformin;   Drug: Glimepiride and metformin 
 
 

 
82
Recruiting
Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are Obese
Conditions:
Abdominal Obesity;   Growth Hormone Deficiency 
Interventions:
Drug: Growth hormone releasing hormone (GHRH) 1-44;   Drug: Placebo 
 
 

 
83
Recruiting
Effects of Rosuvastatin on Aortic Stenosis Progression
Condition:
Aortic Stenosis 
Interventions:
Drug: Rosuvastatin;   Drug: Placebo 
 
 

 
84
Recruiting
Effects of Low and Moderate Fat Diets on Lipids, Inflammation and Vascular Reactivity in the Metabolic Syndrome
Conditions:
Metabolic Syndrome X;   Dyslipidemias 
Interventions:
Behavioral: Moderate Fat and Moderate Carbohydrate Diet;   Behavioral: Low Fat and High Carbohydrate Diet 
 
 

 
85
Recruiting
Long Terms Outcomes of Two Treatment Approaches for Obese Women
Condition:
Obesity 
Interventions:
Behavioral: Wellness-Centered (HUGS);   Behavioral: Weight-Centered (LEARN) 
 
 

 
86
Recruiting
China Intensive Lipid Lowering With Statins in Acute Coronary Syndrome
Condition:
Acute Coronary Syndrome 
Interventions:
Drug: Atorvastatin;   Drug: Atorvastatin 
 
 

 
87
Recruiting
Effects of Nicotinic Acid Plus Simvastatin Versus Simvastatin Alone on Carotid and Femoral Intima-Media Thickness in Patients With Peripheral Artery Disease (NASCIT) -A RCT
Conditions:
Dyslipidemia;   Atherosclerosis 
Intervention:
Drug: nicotinic acid in addition to simvastatin 
 
 

 
88
Recruiting
Evaluating Simvastatin's Potential Role in Therapy
Condition:
Alzheimer Disease 
Interventions:
Drug: Simvastatin;   Drug: Placebo 
 
 

 
89
Recruiting
Statin Therapy for Ischemic and Nonischemic Cardiomyopathy
Conditions:
Cardiovascular Disease;   Cardiomyopathy;   Heart Disease;   Myocardial Disease;   Myocardial Ischemia 
Intervention:
Drug: Atorvastatin Calcium 
 
 

 
90
Recruiting
A Randomized Controlled Trial of High Dietary Fiber Intake on Serum Lipids
Condition:
Hyperlipidemia 
Intervention:
Dietary Supplement: Uncle Sam Cereal 
 
 

 
91
Recruiting
The Effect of Palm Olein, Olive Oil and Lard and on Risk Markers of Cardiovascular Disease
Conditions:
Cardiovascular Disease;   Metabolic Syndrome 
Intervention:
Other: Palm olein vs olive oil and lard 
 
 

 
92
Recruiting
Lipid Metabolism in Gestational Diabetes
Conditions:
Gestational Diabetes;   Hyperlipidemia 
Intervention:
Other: lipid blood testing 
 
 

 
93
Recruiting
Compare the Efficacy of Rosuvastatin to Atorvastatin in High Risk Patients With Hypercholesterolemia
Condition:
Hypercholesterolemia 
Interventions:
Drug: rosuvastatin;   Drug: Atorvastatin 
 
 

 
94
Recruiting
Thyroid and Glucose and Energy Metabolism
Conditions:
Thyroid Diseases;   Thyroidectomy;   Replacement Thyroid Hormone Therapy;   Near Total Thyroidectomy 
Interventions:
Drug: Liothyronine (T3);   Drug: Levothyroxine (T4) 
 
 

 
95
Recruiting
Naturopathic Treatment for the Prevention of Cardiovascular Disease
Condition:
Cardiovascular Disease 
Interventions:
Other: Naturopathic medicine. May include: fish oil, plant sterols, soluble fiber, cinnamon, coQ10 and exercise;   Other: Conventional medical treatment (Atorvastatin,Fluvastatin,Lovastatin,Pravastatin,Rosuvastatin,Simvastatin) 
 
 

 
96
Recruiting
A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction
Conditions:
Hyperlipidemia;   Hypercholesterolemia 
Interventions:
Drug: ezetimibe;   Drug: niacin;   Drug: colestipol 
 
 

 
97
Recruiting
Prevalence of Metabolic Syndrome in OSA and Effect of Treatment With Auto-CPAP (Continuous Positive Airway Pressure) on Metabolic Syndrome
Conditions:
Obstructive Sleep Apnea;   Metabolic Syndrome 
Interventions:
Device: AutoSet Spirit--Wash--Modified-AutoSet Spirit;   Device: Modified-AutoSet Spirit--Wash-AutoSet Spirit 
 
 

 
98
Recruiting
Japan Statin Treatment Against Recurrent Stroke (J-STARS)
Condition:
Ischemic Stroke 
Intervention:
Drug: Pravastatin 
 
 

 
99
Recruiting
Pioglitazone as a Treatment for Lipid and Glucose Abnormalities In Patients With Schizophrenia
Conditions:
Diabetes;   Schizophrenia;   Insulin Resistance;   Cognitive Impairment 
Interventions:
Drug: Pioglitazone;   Behavioral: Life style diet group;   Other: placebo 
 
 

 
100
Not yet recruiting
Effects of Mixed Exercise Regime and L-Carnitine Supplementation in HIV Patients on HAART
Conditions:
HIV Infections;   Hyperlipidemia;   Exercise 
Intervention:
Dietary Supplement: l-carnitine 
 
 
101
Recruiting
Testosterone Replacement in Older Men and Atherosclerosis Progression
Conditions:
Hypogonadism;   Atherosclerosis 
Intervention:
Drug: Testosterone Gel (Androgel) 
 
 

 
102
Recruiting
Measure Liver Fat Content After ISIS 301012 Administration
Conditions:
Lipid Metabolism, Inborn Errors;   Hyperlipidemias;   Metabolic Diseases;   Hypolipoproteinemia;   Hypolipoproteinemias;   Hypobetalipoproteinemias;   Metabolism, Inborn Errors;   Genetic Diseases, Inborn;   Infant, Newborn, Diseases;   Congenital Abnormalities;   Metabolic Disorder;   Hypercholesterolemia;   Dyslipidemias;   Lipid Metabolism Disorders 
Interventions:
Drug: mipomersen sodium;   Drug: Placebo;   Drug: mipomersen sodium;   Drug: placebo;   Drug: mipomersen sodium;   Drug: placebo 
 
 

 
103
Recruiting
Effect of Physical Activity on Metabolic Syndrome in Pregnancy & Fetal Outcome
Conditions:
Obesity;   Pregnancy;   Diabetes Mellitus 
Intervention:
Behavioral: Experimental group 
 
 

 
104
Recruiting
COACH - Community Outreach And Cardiovascular Health
Conditions:
Cardiovascular Disease;   Diabetes 
Intervention:
Behavioral: lifestyle and medication prescription 
 
 

 
105
Recruiting
Study of the Effects of a Mineralized Water Ingestion Upon Lipidic Absorption Mechanisms
Condition:
Moderated Cholesterolemia 
Interventions:
Other: Mineralized water;   Other: Low mineralized water 
 
 

 
106
Recruiting
Improving Risk Factors for Diabetes Complications in Primary Care
Condition:
Type 2 Diabetes 
Intervention:
Behavioral: Practice Facilitation 
 
 

 
107
Recruiting
 

 
108
Recruiting
Effects of 2 Initial Standard Antiretroviral Combinations Therapies on Lipid Metabolism
Condition:
HIV Infections 
Interventions:
Drug: Tenofovir + emtricitabine + efavirenz;   Drug: Tenofovir + emtricitabine + lopinavir/ritonavir 
 
 

 
109
Recruiting
Effect of Rosuvastatin on Lipid Levels in Patients With Metabolic Syndrome
Condition:
Metabolic Syndrome 
Intervention:
Drug: rosuvastatin 
 
 

 
110
Recruiting
Evaluation of Endocrine and Metabolic Parameters in the New Diagnostic Phenotypes of Polycystic Ovary Syndrome
Condition:
Polycystic Ovary Syndrome 
Intervention:
Procedure: Blood samples, transvaginal ultrasound 
 
 

 
111
Recruiting
Safety and Efficacy of ISIS 301012 (Mipomersen) As Add-on Therapy in High Risk Hypercholesterolemic Patients
Conditions:
Hypercholesterolemia;   Coronary Heart Disease 
Interventions:
Drug: Mipomersen sodium;   Drug: Placebo 
 
 

 
112
Recruiting
Lipoprotein Turnover on Low- and High-MUFA Portfolio Diets
Conditions:
Hyperlipidemia;   Cardiovascular Diseases;   Diet Therapy 
Intervention:
Procedure: low or high MUFA portfolio diets 
 
 

 
113
Recruiting
Add-on Simvastatin in Schizophrenia Trial
Condition:
Schizophrenia 
Intervention:
Drug: Simvastatin 
 
 

 
114
Recruiting
Safety and Efficacy Study of 301012 Administration in High Risk Statin Intolerant Subjects
Conditions:
Metabolic Diseases;   Hyperlipidemias;   Metabolic Disorder;   Hypercholesterolemia;   Dyslipidemias;   Lipid Metabolism Disorders 
Interventions:
Drug: mipomersen sodium (ISIS 301012);   Drug: placebo saline 
 
 

 
115
Recruiting
Causes and Natural History of Dyslipidemias
Condition:
Dyslipidemias 
Intervention:
 
 
 

 
116
Recruiting
A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis
Conditions:
Coronary Heart Disease;   Diabetes Mellitus;   Non-Coronary Atherosclerotic Disease;   Hypercholesterolemia 
Intervention:
Drug: Atorvastatin, Ezetimibe 
 
 

 
117
Recruiting
Effectiveness of Pulse-Based Foods Combined With Exercise for Improving Components of the Metabolic Syndrome
Condition:
Metabolic Syndrome 
Interventions:
Behavioral: Aerobic exercise training;   Dietary Supplement: pulse based diet 
 
 

 
118
Recruiting
Smoking Cessation With Smokeless Tobacco, Nicotine Tablets and Nicotine Patches
Condition:
Tobacco Dependence 
Interventions:
Drug: Smokeless tobacco (Oliver Twist pellets);   Behavioral: smoking cessation counseling 
 
 

 
119
Recruiting
Assessing the Effectiveness of Concurrent Peer Review for Patients With Cardiovascular Disease and Diabetes
Condition:
Cardiovascular Diseases 
Interventions:
Other: Usual Care;   Behavioral: Active 
 
 

 
120
Recruiting
Ezetimibe and Statins on Postprandial Lipemia in Type 2 Diabetes
Conditions:
Postprandial Lipemia;   Type 2 Diabetes 
Intervention:
Drug: ezetimibe - simvastatin 
 
 

 
121
Recruiting
Abdominal Obesity and Cardiovascular Risk Factors in Women Who Survived Leukemia Following Total Body Irradiation and Stem Cell Transplant
Condition:
Leukemia 
Intervention:
Other: Questionnaires, Laboratory tests, Abdominal MRI 
 
 

 
122
Recruiting
Necessity for Lipid Lowering Therapy in Type 2 Diabetes Patients
Condition:
Type 2 Diabetes 
Intervention:
Other: Stop lipid lowering therapy (statin) 
 
 

 
123
Not yet recruiting
Combining Acitretin and Efalizumab in the Therapy of Chronic Plaque Psoriasis
Condition:
Chronic Plaque Psoriasis 
Interventions:
Drug: efalizumab plus placebo;   Drug: efalizumab plus acitretin 
 
 

 
124
Recruiting
Effect of a Mediterranean Diet and Omega-3 Fatty Acids on Oxidative Stress and Endothelial Progenitor Cells (EPC's)
Condition:
Obesity 
Interventions:
Behavioral: Diet, Mediterranean;   Drug: Omega-3 Fatty Acids 
 
 

 
125
Recruiting
LOADD (Lifestyle Over and Above Drugs in Diabetes) Study
Condition:
Type 2 Diabetes Mellitus 
Intervention:
Behavioral: Intensive dietary advice 
 
 

 
126
Not yet recruiting
Pioglitazone Therapy in Obese Children With Insulin Resistance: A Randomized, Controlled Pilot Study
Conditions:
Obesity;   Insulin Resistance 
Interventions:
Drug: pioglitazone;   Drug: placebo 
 
 

 
127
Not yet recruiting
Walnut Intervention on Metabolic Syndrome (WIMS)
Condition:
Metabolic Syndrome X 
Interventions:
Dietary Supplement: walnut;   Behavioral: TLC diet education 
 
 

 
128
Recruiting
A Study of MCI-196 in Chronic Kidney Disease Subjects on Dialysis With Hyperphosphatemia and Dyslipidaemia
Conditions:
Chronic Kidney Disease;   Dialysis;   Hyperphosphatemia;   Dyslipidemia 
Interventions:
Drug: MCI-196 (Colestilan(INN), Colestimide(JAN), CHOLEBINE®);   Drug: Placebo 
 
 

 
129
Recruiting
Culturally-Tailored Approach to Improve Medication Use in Patients With Heart Attacks
Conditions:
Coronary Arteriosclerosis;   Myocardial Infarction 
Interventions:
Behavioral: Navigation by a health worker;   Behavioral: Information control 
 
 

 
130
Recruiting
Cardio Risk of Acute Schizophrenia Olanzapine Duke
Conditions:
Schizophrenia;   Schizoaffective Disorder 
Interventions:
Drug: Olanzapine;   Drug: Metformin;   Drug: Simvastatin 
 
 

 
131
Recruiting
Cardiovascular Risk Factor Management in HIV Infection
Conditions:
Coronary Heart Disease;   Dyslipidemia;   Diabetes Mellitus, Non-Insulin-Dependent;   HIV Infection 
Intervention:
Behavioral: Provision of computer generated CHD risk profiles 
 
 

 
132
Recruiting
The Effect of Diet and Exercise in Heart Failure
Conditions:
Heart Failure, Congestive;   Metabolic Syndrome X;   Obesity 
Intervention:
Behavioral: Lifestyle Modification (diet, exercise, and behavior) 
 
 

 
133
Not yet recruiting
Improving Medication Adherence Through Graphically Enhanced Interventions in Acute Coronary Syndromes (IMAGE-ACS)
Condition:
Acute Coronary Syndrome (ACS) 
Intervention:
Procedure: Graphic medication schedule (Pill card) 
 
 

 
134
Recruiting
Treatment of Insulin Resistance in Hypertensive, Obese Adolescents
Conditions:
Hypertension;   Insulin Resistance;   Dyslipidemia 
Intervention:
Drug: Telmisartan 
 
 

 
135
Recruiting
The Diabetes Telemonitoring (DiaTel) Study
Condition:
Diabetes 
Interventions:
Behavioral: Active Care Management;   Behavioral: Care Coordination 
 
 

 
136
Not yet recruiting
Evaluation Research of a National Accreditation and Improvement Programme for General Practice
Condition:
Cardiovascular Disease 
Intervention:
Other: National programme for accreditation and improvement of GP 
 
 

 
137
Recruiting
Treating Congestive Heart Failure Using a Device to Remove Cholesterol
Condition:
Heart Decompensation 
Intervention:
Device: Kaneka Liposorber 
 
 

 
138
Recruiting
Compare Effects of a Soluble Fiber on Weight and Blood Cholesterol
Condition:
Obesity 
Interventions:
Dietary Supplement: Y288;   Dietary Supplement: Y288 
 
 

 
139
Recruiting
Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets
Conditions:
Hyperlipidemias;   Atherosclerosis;   Coronary Heart Disease;   Carotid Stenosis;   Peripheral Vascular Diseases;   Diabetes Mellitus 
Intervention:
 
 
 

 
140
Recruiting
Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides.
Conditions:
Insulin Resistance;   Hypertriglyceridemia 
Interventions:
Drug: Rosiglitazone;   Drug: Fenofibrate;   Behavioral: Weight Loss 
 
 

 
141
Recruiting
 

 
142
Recruiting
 

 
143
Recruiting
Hepatitis C Treatment and Atherosclerosis
Conditions:
Chronic Hepatitis C;   Atherosclerosis 
Intervention:
 
 
 

 
144
Recruiting
Study of Women With Acute Coronary Syndromes and Nonobstructive Coronary Artery Disease
Condition:
Acute Coronary Syndromes 
Interventions:
Procedure: Intravascular ultrasound;   Procedure: MRI 
 
 

 
145
Not yet recruiting
Does Coenzyme Q 10 Supplementation Reduces Muscle Pain Caused by Statins? (Cholesterol Lowering Medications)
Condition:
Statin Induced Myalgia 
Interventions:
Drug: Coenzyme Q 10;   Drug: Placebo control 
 
 

 
146
Recruiting
Targeting Inflammation Using Salsalate for Type 2 Diabetes-Stage II
Condition:
Type 2 Diabetes Mellitus 
Interventions:
Drug: Salsalate;   Drug: Salsalate Placebo 
 
 

 
147
Recruiting
Pitavastatin on Carotid Intima-Media Thickness
Conditions:
Hyperlipidemia;   Carotid Artery Diseases 
Interventions:
Drug: Pitavastatin;   Drug: Pitavastatin 
 
 

 
148
Not yet recruiting
Lifestyle Intervention Targetting Obesity and Insulin Resistance in Chronic Hepatitis C
Conditions:
Obesity;   Insulin Resistance;   Metabolic Syndrome;   Hepatitis C 
Intervention:
Other: Lifestyle intervention 
 
 

 
149
Recruiting
The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's Disease
Conditions:
Alzheimer Disease;   Hypercholesterolemia 
Interventions:
Drug: Pitavastatin;   Drug: cholesterol-lowering medicine other than statin 
 
 

 
150
Recruiting
Effectiveness of Candesartan and Telmisartan on Morning Hypertension in Japanese Obese Patients
Condition:
Hypertension 
Interventions:
Drug: Candesartan;   Drug: Telmisartan